1. Researchers at Stanford devised a strange new molecule that could lead to drugs that arm genes and make cancers work against themselves. Within every cancer are molecules that spur deadly, uncontrollable growth. What if scientists could hook those molecules to others that make cells self-destruct? Could the very drivers of a cancer’s survival instead activate the program for its destruction? That idea came as an epiphany to Dr. Gerald Crabtree, a developmental biologist at Stanford, some years ago during a walk through the redwoods near his home in the Santa Cruz mountains. “I ran home,” he said, excited by the idea and planning ways to make it work. Now, in a paper published Wednesday in the journal Nature, Dr. Crabtree, a founder of Foghorn Therapeutics, which is developing cancer drugs, along with Nathanael S. Gray, a professor of chemical and system biology at Stanford, and their colleagues report that they have done what he imagined on that walk. (Source: nytimes.com, nature.com)
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