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A World First.

A dizzying rise.

John Ellis
May 20, 2025
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“It’s the first thing I read every day.” — Brigadier General (retired) Russ Howard, founding director of The Combating Terrorism Center at West Point.


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1. The CRISPR family’s most versatile member has made its medical debut: a cutting-edge gene-editing technique known as prime editing has been used to treat a person for the first time. The recipient is a teenager with a rare immune disorder. Researchers designed the treatment to correct a mutation that causes chronic granulomatous disease, a dangerous condition that disables a variety of immune cells, including those called neutrophils. A month after the teenager received the treatment, he had experienced no serious side effects. And the therapy seemed to have restored the function of a crucial enzyme in two-thirds of his neutrophils — more than enough to provide a significant boost to his immune system. (Source: nature.com)


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